Publication Type: Journal Article
Source: Biomed Data J., Volume 1, Issue 3, p.41-44 (2015)
Keywords: cardiac remodelling
, Heart Failure
, myocardial infarction
The simulation of the time course of development of heart failure after an acute myocardial infarction requires large, open-access datasets. In this report, we present large echocardiographic datasets of cardiac function in rats after myocardial infarction at two different time points (2 and 13 weeks). We present measurements that show the deterioration of global left ventricular (LV) function, regional function, development of LV dilation, reactive hypertrophy and changes in LV geometry. We present in addition measurements showing the degree of cardiac injury assessed by the area and weight of the scar tissue.These data represent the progressive nature of cardiac remodelling and could be used to build computational models to predict the development of heart function deterioration based on the extent of myocardial injury and the development of LV remodelling.