Top papers

# File Name Number of Downloadssort ascending
1 BMDJ_template_Policy_paper_16.docx 9770
2 BMDJ_template_Data_paper_16.docx 8005
3 BMDJ_template_Modelling_paper_16.docx 7945
4 BMDJ_template_Editorial_16.docx 7195
5 bmdj.01102_ec_oa_policy_horizon2020.pdf 6946
6 BMDJ_template_Commentary_16.docx 6520
7 bmdj.01103_comp_modelling_cancer.pdf 6060
8 bmdj.01301_Mice_Myocardial_Infarction.pdf 5137
9 bmdj.01108_legal_challenges.pdf 4839
10 01300_Heart_Failure_and_Stress_Response.pdf 4758
11 posture.05.pdf 4537
12 bmdj.01101_oa_to_scien_info.pdf 4497
13 bmdj.01304_Vassalle_Anaemia_Predictor.pdf 4441
14 bmdj.01303_Circulatory_modelling.pdf 4411
15 bmdj.01302_Rat_AMI_Dataset.pdf 4059
16 bmdj.01305_Cardiac_Magnetic_Resonance_Imaging.pdf 3983
17 bmdj.01109_osl_platform.pdf 3307
18 bmdj.01100_editorial_pilot.pdf 3307
19 bmdj.01106_oa_cardiology_research.pdf 3299
20 bmdj.01107_oa_drug_discovery.pdf 3176
21 bmdj.01104_clinical_brain_research.pdf 3148
22 bmdj.01204_Thyroid_Hormone_Ischemic_Stroke.pdf 3147
23 posture.03.pdf 3016
24 bmdj.01105_oa_endocrine_research.pdf 2948
25 posture.07.pdf 2933
Computational Modelling in Cancer: Methods and Applications The Hallmarks of Cancer, Hallmarks of Cancer: The Next Generation, Lessons from Hereditary Colorectal Cancer, Creation of Human Tumour Cells with Defined Genetic Elements, Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorigenesis., Cancer: A Systems Biology Disease, Cancer systems biology and modeling: Microscopic scale and multiscale approaches, Multiscale Computational Models of Complex Biological Systems, Computational Modeling and Simulation as Enablers for Biological Discovery, Computational systems biology in cancer: modeling methods and applications., In silico cancer modeling: is it ready for prime time?, In silico models of cancer, Multiscale Models of Breast Cancer Progression, Using computational modeling to assess the impact of clinical decision support on cancer screening improvement strategies within the community health centers, Predictive medicine: computational techniques in therapeutic decision-making., PubMed and beyond: a survey of web tools for searching biomedical literature, Simulating cancer growth with multiscale agent-based modeling, Multiscale Cancer Modeling, Circuit simulation of genetic networks, Computational modeling of brain tumors: discrete, continuum or hybrid?, The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models, Systems Biology Markup Language (SBML), Systems biology markup language: Level 2 and beyond., UML as a cell and biochemistry modeling language, The IUPS human physiome project, CellML: its future, present and past, An Overview of CellML 1.1, a Biological Model Description Language, Specifications of insilicoML 1.0: A Multilevel Biophysical Model Description Language, FieldML, a proposed open standard for the Physiome project for mathematical model representation, The SBML ODE Solver Library: a native API for symbolic and fast numerical analysis of reaction networks, MathSBML: a package for manipulating SBML-based biological models, SBMLToolbox: an SBML toolbox for MATLAB users, SBML-PET: a Systems Biology Markup Language-based parameter estimation tool, The SBW-MATLAB interface, Dealing with Diversity in Computational Cancer Modeling, TumorML: Concept and requirements of an in silico cancer modelling markup language, Petri Net representations in systems biology., Petri net representations in metabolic pathways., Petri Nets Are a Biologist’s Best Friend, System modelling with high-level Petri nets, Steady state analysis of metabolic pathways using Petri nets., Application of Petri net based analysis techniques to signal transduction pathways, Application of Petri net based analysis techniques to signal transduction pathways, Petri net modelling of biological networks, Cellular automata approaches to biological modeling., A cellular automata model of diffusion in aqueous systems, A cellular automata model of enzyme kinetics., Cellular automaton models of tumor development: a critical review, An evolutionary hybrid cellular automaton model of solid tumour growth, A hybrid cellular automaton model of clonal evolution in cancer: The emergence of the glycolytic phenotype, Using an agent-based model to analyze the dynamic communication network of the immune response, An agent-based model of inflammation and fibrosis following particulate exposure in the lung, Toward a Multi-Scale Computational Model of Arterial Adaptation in Hypertension: Verification of a Multi-Cell Agent Based Model, A hybrid continuum-discrete modelling approach to predict and control angiogenesis: analysis of combinatorial growth factor and matrix effects on vessel-sprouting morphology, An Agent-Based Model for the Investigation of Neovascularization Within Porous Scaffolds, Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation, Simulating the impact of a molecular 'decision-process' on cellular phenotype and multicellular patterns in brain tumors., Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network, Modeling the cell division cycle: cdc2 and cyclin interactions., Modeling the cell division cycle, A synthetic oscillatory network of transcriptional regulators, Systems Biology: A Brief Overview, Computational systems biology, Modeling and simulation in signal transduction pathways: a systems biology approach, The Meaning of Systems Biology, Computational Modeling of Solid Tumor Growth: The Avascular Stage, Mathematical Modeling of Tumor Growth and Metastatic Spreading: Validation in Tumor-Bearing Mice, Advancing cancer systems biology: introducing the Center for the Development of a Virtual Tumor, CViT., The effects of EGF-receptor density on multiscale tumor growth patterns, Reaction-diffusion model for the growth of avascular tumor, Cellular Potts Modeling of Tumor Growth, Tumor Invasion, and Tumor Evolution, Modeling the Effect of Deregulated Proliferation and Apoptosis on the Growth Dynamics of Epithelial Cell Populations In Vitro, A cellular automata model of tumor–immune system interactions, Nonlinear simulation of tumor necrosis, neo-vascularization and tissue invasion via an adaptive finite-element/level-set method, Computer simulation of glioma growth and morphology, Three-dimensional multispecies nonlinear tumor growth—I: model and numerical method, Hybrid models of tumor growth, A hybrid model for tumor spheroid growth in vitro I: theoretical development and early results, Multiscale modelling and nonlinear simulation of vascular tumour growth, A computer algorithm describing the process of vessel formation and maturation, and its use for predicting the effects of anti-angiogenic and anti-maturation therapy on vascular tumor growth, Expression of hypoxia-inducible factor 1: mechanisms and consequences, Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression., A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 , Effect of Tumor Microenvironment on Tumor VEGF During Anti-VEGF Treatment: Systems Biology Predictions, Mapping the cancer genome. Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies. (3) K. Kourou; D.I. Fotiadis
Cardiac models in drug discovery and development: a review. (6) R.K. Amanfu; J.J. Saucerman
A novel computational model of the human ventricular action potential and Ca transient (12) E. Grandi; F.S. Pasqualini; D.M. Bers
Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. (26) H.P. Adams; B.H. Bendixen; L.J. Kappelle; J. Biller; B.B. Love; D.L. Gordon; E.E. Marsh
A Dataset from Echocardiographic Assessment of Cardiac Function in Mice after Myocardial Infarction Late Cardiac Remodeling After Primary Percutaneous Coronary Intervention, Heart failure post-myocardial infarction: a review of the issues, Cardiac models in drug discovery and development: a review., Thyroid hormone improves the mechanical performance of the post-infarcted diabetic myocardium: A response associated with up-regulation of Akt/mTOR and AMPK activation, Translating thyroid hormone effects into clinical practice: the relevance of thyroid hormone receptor α1 in cardiac repair, The Beneficial Effects of Ranolazine on Cardiac Function After Myocardial Infarction Are Greater in Diabetic Than in Nondiabetic Rats, Inhibition of thyroid hormone receptor α1 impairs post-ischemic cardiac performance after myocardial infarction in mice, Dose-dependent effects of thyroid hormone on post-ischemic cardiac performance: potential involvement of Akt and ERK signalings, The VPH-Physiome Project: Standards and Tools for Multiscale Modeling in Clinical Applications, Models of cardiac excitation–contraction coupling in ventricular myocytes, A model for human ventricular tissue, A Computational Model of the Human Left-Ventricular Epicardial Myocyte, A novel computational model of the human ventricular action potential and Ca transient (5) I. Mourouzis; P. Mantzouratou; C. Pantos
Thyroid Hormone and C-Reactive Protein Serum Concentrations, Disease Severity and Discharge Outcomes of Ischemic Stroke Patients: A Dataset The world health report 2007: a safer future: global public health security in the 21st century, Executive summary: heart disease and stroke statistics-2014 update: a report from the American Heart Association, Percutaneous vascular stent: experimental studies and preliminary clinical results in peripheral arterial diseases., Blood Biomarkers of Ischemic Stroke, The Potential Roles of 18F-FDG-PET in Management of Acute Stroke Patients, Role of N-Terminal Pro-B-Type Natriuretic Peptide, High-Sensitivity C-Reactive Protein, and Inteleukin-6 in Predicting a Poor Outcome after a Stroke, Neuroprotective actions of thyroid hormones and low-T3 syndrome as a biomarker in acute cerebrovascular disorders, Mechanisms behind the non-thyroidal illness syndrome: an update, Nonthyroidal illness syndrome, Intracellular pathways of iodothyronine metabolism, Thyroid disease and mental disorders: cause and effect or only comorbidity?, Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases., Molecular Basis for Certain Neuroprotective Effects of Thyroid Hormone, Intracellular pathways of iodothyro-nine metabolism, Low Free Triiodothyronine Levels are Related to Poor Prognosis in Acute Ischemic Stroke, Low triiodothyronine: a strong predictor of outcome in acute stroke patients., Post-ischaemic thyroid hormone treatment in a rat model of acute stroke, Clinical Analysis on Alteration of Thyroid Hormones in the Serum of Patients with Acute Ischemic Stroke, Anterior pituitary axis hormones and outcome in acute ischaemic stroke, Evaluation of C-reactive protein measurement for assessing the risk and prognosis in ischemic stroke: a statement for health care professionals from the CRP Pooling Project members., C-reactive protein in the very early phase of acute ischemic stroke: association with poor outcome and death, Tumor necrosis factor: a putative mediator of the sick euthyroid syndrome in man., Relating circulating thyroid hormone concentrations to serum interleukins-6 and -10 in association with non-thyroidal illnesses including chronic renal insufficiency, Relationship of circulating C-reactive protein levels to thyroid status and cardiovascular risk in hyperlipidemic euthyroid subjects: low free thyroxine is associated with elevated hsCRP., Reliability of Scandinavian Neurological Stroke, Recovery of motor function after stroke., Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment., "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician., Cognitive Outcomes of Acute Ischemic Stroke Pa-tients: Association with Concentrations of Thyroid Axis Hormones and C-Reactive Protein, Functional outcome of acute ischemic stroke pa-tients: association with concentrations of thyroid hormones and C-reactive protein, Ischemic stroke functional outcomes are independently associated with C-reactive protein concentrations and cognitive outcomes with triiodothyronine concentrations: a pilot study (2) A. Bunevicius; H. Kazlauskas; N. Raskauskiene; V. Janusonis; R. Bunevicius
Inhibition of thyroid hormone receptor α1 impairs post-ischemic cardiac performance after myocardial infarction in mice (6) I. Mourouzis; E. Kostakou; G. Galanopoulos; P. Mantzouratou; C. Pantos
Clinical Analysis on Alteration of Thyroid Hormones in the Serum of Patients with Acute Ischemic Stroke (17) Y. Zhang; M.A. Meyer
Design of the Reduction of Events with Darbepoetin alfa in Heart Failure (RED-HF): a Phase III, anaemia correction, morbidity-mortality trial (19) J.J.V. McMurray; I.S. Anand; R. Diaz; A.P. Maggioni; C. O'Connor; M.A. Pfeffer; K.R. Polu; S.D. Solomon; Y. Sun; K. Swedberg; M. Tendera; D.J. van Veldhuisen; S.M. Wasserman; J.B. Young
Effects of Acute Transcutaneous Vagal Stimulation on the EEG Power Maps, EEG Sources Distribution and Steadiness of Quiet and Sensory-conflicted Stance Transcutaneous vagus nerve stimulation for partial onset seizure therapy, Transcutaneous vagus nerve stimulation (t-VNS) in pharmacoresistant epilepsies: A proof of concept trial, Transcutaneous auricular vagus nerve stimulation as a complementary therapy for pediatric epilepsy: A pilot trial, Auricular transcutaneous electrical nerve stimulation in depressed patients: a randomized controlled pilot study, The effect of transcutaneous vagus nerve stimulation on pain perception – An experimental study, Surgically implanted and non-invasive vagus nerve stimulation: a review of efficacy, safety and tolerability, A sensory cortical representation of the vagus nerve with a note on the low pressure on the surface electrogram, Review of the Mechanisms of Action of Antiepileptic Drugs, Brainstem Vagus nuclei evoked potentials – a new diagnostic method in neuropsychiatry?, Vagus somatosensory evoked potentials are delayed in Alzheimer’s disease, but not in major depression, Central Neural Versus Peripheral Muscular Origin of Vagus Somatosensory – Evoked Potentials, Vagal Sensory Evoked Potentials Disappear Under the Neuromuscular Block – An Experimental Study, On the Origin of Scalp Responses – A Comment on the Letter of Polak et al., Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain, EEG source imaging, Review of methods for solving the EEG inverse problem, Chronic vagus nerve stimulation for treatment-resistant depression increases regional cerebral blood flow in the dorsolateral prefrontal cortex, Is the pain in chronic pancreatitis of neuropathic origin? Support from EEG studies during experimental pain, Transcutaneous Vagus Nerve Stimulation Modulates Tinnitus-Related Beta- and Gamma-Band Activity, Cerebral processing of painful oesophageal stimulation: a study based on independent component analysis of the EEG, New technologies to investigate the brain-gut axis, Enhanced recognition memory following vagus nerve stimulation in human subjects, Transcutaneous Vagal Nerve Stimulation (tVNS): a new neuromodulation tool in healthy humans?, Therapeutic mechanisms of vagus nerve stimulation, How do you feel? Interoception: the sense of the physiological condition of the body, Gut feelings: the emerging biology of gut–brain communication, Scalp-Recorded Evoked Potentials as a Marker for Afferent Nerve Impulse in Clinical Vagus Nerve Stimulation, Reversing pathological neural activity using targeted plasticity, Repeatedly Pairing Vagus Nerve Stimulation with a Movement Reorganizes Primary Motor Cortex, Pairing tone trains with vagus nerve stimulation induces temporal plasticity in auditory cortex, Vagus nerve stimulation during rehabilitative training improves forelimb strength following ischemic stroke, Pairing Speech Sounds With Vagus Nerve Stimulation Drives Stimulus-specific Cortical Plasticity, Targeting plasticity with vagus nerve stimulation to treat neurological disease. (5) B. Dimitrov; P. Gatev